Review Article


Comparison of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) and portal vein embolization (PVE) in the management of advanced liver tumors

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1 School of Medicine, University College of Cork, Cork, Ireland

Address correspondence to:

Lim Ai Ying Hannah

Bramley 1, Apartment 10, Orchard Gardens, Dennehys Cross, Cork,

Ireland

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Article ID: 100006G02JL2021

doi: 10.5348/100006G02JL2021RV

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How to cite this article

Lee JKH, Low KJC, Lim BPY, Hannah LAY. Comparison of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) and portal vein embolization (PVE) in the management of advanced liver tumors. Edorium J Gastrointest Surg 2021;6:100006G02JL2021.

ABSTRACT


Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a relatively new procedure in the management of advanced liver tumors. However, there is limited literature on its benefits over its predecessor—Portal vein embolization (PVE). This review article aims to highlight various aspects of ALPPS and PVE including: (a) patient selection, (b) surgical technique, (c) assessment of volume, growth and function of liver, (d) morbidity and mortality, and (e) oncological outcomes. This could guide surgical clinicians in selecting their approach (ALPPS or PVE) when managing advanced liver tumors.

Keywords: Advanced liver tumors, Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS), Hepatocellular carcinoma (HCC), Portal vein embolization (PVE)

SUPPORTING INFORMATION


Author Contributions

Jeremy Kay Hock Lee - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Kenneth Jun Chuen Low - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Bryant Po Yuen Lim - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Lim Ai Ying Hannah - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2021 Jeremy Kay Hock Lee et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.


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